The Effect of Garcinia (Garcinia cambogia) and Green Coffee on Obese Rats

Document Type : Original research articles

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Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shebin El-Kom, Egypt

Abstract

The
current study was designed to investigate the effects of green coffee and Garcinia cambogia on weight loss in obese rats. Forty-eight male Sprague Dawley rats weighing between 150 and 160 grams were randomly divided into eight groups as follows: the first group consisted of a negative control group fed a basic diet (6 rats), while the second group consisted of obese groups (42 rats). Obesity was induced by feeding them 200 grams of fat in addition to the main diet for twenty days. They were then divided into seven subgroups (6 rats each): the first group was the positive control group; the second group of obese rats was fed a standard diet and 1.5% green coffee powder by weight of the diet; the third group was fed a standard diet and 3% green coffee powder by weight; the fourth group was fed a standard diet and 1.5% Garcinia powder by weight; the fifth group was fed a standard diet and 3% Garcinia powder by weight; the sixth group was fed a standard diet with a Mixture ture of green coffee and Garcinia powder at 1.5% by weight; and the seventh group was fed a standard diet with a Mixture ture of green coffee and Garcinia powder at 3% by weight. The study period was 28 days. The results indicated that both green coffee and Garcinia, especially at higher doses and in combination, significantly improved lipid levels, reduced the atherogenic index, improved leptin levels, and enhanced insulin sensitivity in obese male rats.

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