Hypouricemic Effect of Moringa Oleifera Leaves and Ginger (Zingiber Officinale Rosc.) Powders in Male Albino Rats

Document Type : Original research articles

Authors

Department of Nutrition and Food Science,Faculty of Home Economics,Menoufia University, Shebin El-Kom, Egypt.

Abstract

This study aimed to examine the effect of Moringa leaves (M) and ginger (G) powders on Hyperuricemic albino rats. Chemical analyses of powders Moringa leaves and ginger powders were conducted. Forty-eight adult male laboratory rats were used, and their weight was (200 ± 2g). Twelve groups have been divided, including a control group (four rats/group). All groups were injected with Gentamicin (100 mg/kg of body weight) daily for seven days except the control group. The powders at percent (2% and 4%) of M or ginger and their mixtures were added in a ratio ((1:1), (2:1), (1:2)) from the basal diet. After 4 weeks, the mice were slaughtered. Then, body weight, weight of heart, liver, kidney, and spleen, level of glucose in serum, kidney functions, albumin, globulin, and total protein were estimated. Then, statistical analysis was conducted. This study showed that the M or G separately or in combination significantly improves body weight, organ weight, serum glucose, kidney functions, albumin, globulin, and total protein. In contrast, there was significant progress in blood glucose levels in the 2% Moringa-fed group. Also, there were significant improvements in body weight gain, feed efficiency ratio, kidney functions, albumin, globulin, total protein, liver, and kidney weight in the group fed on Ginger 4%. Meanwhile, the mixture at 4% (2M: 1G) has significantly improved all parameters of hyperuricemic albino rats. This review found a statistical significance that a mixture at 4% (2M: 1G) may improve the health status of Hyperuricemic albino rats.

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