Hypouricemic Effect of Moringa Oleifera Leaves and Ginger (Zingiber Officinale Rosc.) Powders in Male Albino Rats

Document Type : Original research articles

Authors

1 Dept. Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt

2 Department of Nutrition and Food Science,Faculty of Home Economics,Menoufia University, Shebin El-Kom, Egypt.

3 Faculty of Home Economics,Menoufia University

Abstract

This study amied to examine the effect of leaves of Moringa (M) and ginger (G) powder on the mice infected Hyperuricemia. Chemical analyzes of powders Moringa leaves and ginger was conducted. 48 adult male of laboratory rat, were used their weight were (200 ± 2g). Twelve groups include control group (four mice/group) have been divided. All groups were injected by Gentamicin (100 mg/kg of body weight) daily for seven days except control group. The powders at percent (2%, 4%) of M and ginger and their mixtures were added in a ratio ((1:1), (2:1), (1:2)) from the Basel diet. After 4 weeks the mice were slaughtered then it was estimated, body weight, weight of Heart, Liver, Kidney and Spleen, level of glucose in blood, kidney functions, albumin, globulin ,total protein. Then, statistical analysis was conducted. Results: this study showed that the M or G separately or in combination significantly improve the body weight, Organs weight, serum glucose, kidney functions, albumin, globulin and total protein. While there was significant progress in blood glucose levels at the 2% Moringa fed group. Also there were significant improvements at body weight gain, feed essential ratio kidney functions, albumin, globulin, total protein and, Liver and Kidney weight at the group fed on Ginger 4%. While mixture at 4% (2M: 1G), have been more significant improved in all parameters Hyperuricemic albino rats. In conclusion: This review found statistical significance that mixture at 4% (2M: 1G) may improve health status of Hyperuricemic albino rats.

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