Document Type : Original research articles
Authors
1
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
2
Department of Nutrition and Food Sciences, Faculty of Home Economics , Menoufia University,Shibin El Kom, Egypt
Abstract
Most people's which can lead to diseases including diabetes and atherosclerosis. Chemical formulas could have detrimental impacts on health. Meanwhile, The primary objective of the present study is to compare the impact of Chitocal, a combination of herbal ingredients (turmeric and ginger), on obese rats. Forty-eight adult male albino rats were divided into two main groups. The first group, comprising six rats, was the control group, and a basal diet (BD) was provided. The second main group, consisting of forty-two rats, was given a high-fat diet to induce obesity and divided into seven equal subgroups. These subgroups included a positive control group (BD) and groups fed with BD containing 2.5% and 5.0% Critical, herbal mixture, and a combination of both (w/w). After 28 days, the weight gain, food intake, and food efficiency ratio were evaluated. Blood samples were also analyzed to determine the levels of liver enzymes (AST, ALT), lipid profile (T.G., T.C., LDL-c, HDL-c, and VLDL-c), kidney functions (uric acid, urea, and creatinine), glucose levels, and a complete blood count (CBC), including white blood cells (WBC) and red blood cells (RBC). The results revealed that obesity led to disturbances in BWG, FI, and FER. Furthermore, the functions of the liver and kidneys, as well as the lipid profile and glucose levels in the serum, were affected. Treating obese rats with critical herbal mixtures improved all of these parameters.
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