Influence of Burdock and Horsetail in Treatment of Renal Functions Disorder in Gentamicin-Induced Rats

Document Type : Original research articles

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Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt

Abstract

This study examined the effect of various levels of (
Equisetum arvense, L
.) and burdock (
Arctium lappa, L.
) powdered and their mixtures on kidney-damaging rats. Forty-eight male albino rats weighing 160±10g have been used in the current research. There had been eight groups of rats. There are six rats in every group. Normal healthful male albino rats had been given injections of gentamicin at a level of 10 mg/kg b.w. as soon as a day for ten days to induce renal damage, whilst one group was once saved as the control negative. Renal functioning indications (creatinine, urea, and uric acid), glucose level, serum liver enzymes [Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), and Alkaline phosphatase (ALP)], also lipid fraction such as triglyceride (TG), total cholesterol (TC), Low-Density Lipoprotein (LDL-c), Very Low-Density Lipoprotein (VLDL-c), and High-Density Lipoprotein (HDL-c), have also been measured and based on the findings, the kidney and liver biomarkers, glucose range, and lipid profiles of tested rats improved when burdock and horsetail powder were combined. The 4% mixed produced excellent effects and is encouraged as a beverage to enhance renal function. In conclusion, horsetail and burdock should be considered adequate therapeutic spices or food additive regimens for treating renal disorders in rats.

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