Antidiabetic Potential of juniper plants in diabetic rats.

Document Type : Original research articles

Authors

1 Department of Home Economics (Nutrition), Faculty of Science and Arts in Al-Makhwa, AL-Baha University, AlMakhwa, Saudi Arabia

2 partment of Home Economics (Nutrition), Faculty of Science and Arts in Al-Makhwa, AL-Baha University, AlMakhwa, Saudi Arabia

Abstract

Juniper is a coniferous plant classified within the cypress family. Traditionally, juniper has been used for its therapeutic qualities, specifically in treating specific health ailments, such as diabetes. This experiment aims to demonstrate the antidiabetic properties of juniper plants in rats with diabetes. A set of thirty (30) male albino rats of the Sprague-Dawley strain, each weighing 170±10g at ten weeks of age, were divided into four separate groups. The initial group functioned as a negative control, serving as the standard against which the other groups were compared. However, the other groups were exposed to alloxan induction in order to induce diabetes. During the 28-day duration of the trial, individuals in the positive control group with diabetes were administered juniper plants at concentrations of ten percent, twenty percent, and twenty-five percent. After the experiment, the removed organs and blood samples were subjected to biochemical analysis. A notable disparity was seen across the groups before and after the intervention concerning glucose levels (P = 0.005). Group 5, consisting of hyperglycemic rats fed a 25% juniper diet, had the highest blood glucose, HDL, AST, and creatinine levels. Based on these findings, juniper syrup is suggested for those with diabetes to lower LDL atherogenic index values. Additionally, different doses of juniper powder may be advised for specific health conditions related to diabetes

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