Effect of Some Plant Parts (Marjoram and Vitexagnus-Castus) Containing Phytoestrogen on the Ovaries of Female Experimental Rats

Document Type : Original research articles

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Department of Nutrition and Food Science,Faculty of Home Economics, Menoufia University, Shebin El- Kom, Egypt.

Abstract

This research studied the therapeutic effects of marjoram and palm trees and the biological, biochemical, and histopathological changes in the ovaries of female laboratory rat. Thirty rats weighing approximately 150 grams ±10 were used during the experiment and were 3 months old. Concentrates of dried marjoram and palm of Mary were used at concentrations of 5%, 10%, and 2.5% of the basic meal. Rat were fed the basal diet for 5 consecutive days to achieve adaptation. Then, the rats were divided into 6 groups of 30 rats, each group consisting of 5 rat. After conducting the experiment and recording the results, the percentage of estrogen for the negative control group (Group 1) was recorded as (-) the lowest value compared to the rest of the groups, with a significant difference. The value was 4.56%, while the value reached 4.56%. The rats fed (2.5%, 2.5%) recorded the highest estrogen value. The lowest value was recorded with the group fed with 5% vitex agnus-castus compared to the first group (-), with a significant difference, as the values reached (5.3, and16.06), respectively. The lowest value was recorded with the group fed with marjoram, 10%, compared to the first group (-), with a significant difference, as the values reached (7.58 and 6.21), respectively. The histological results confirmed the validity of the chemical analyses on the reproductive system organs (ovaries, ovarian ducts, uterine wall).

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