Effect of some plant parts containing phytoestrogen on the ovaries of female experimental mice

Document Type : Original research articles

Authors

1 Department of Nutrition and Food Science,Faculty of Home Economics, Menoufia University, Shebin El- Kom, Egypt.

2 Faculty of Home Economics, Shebin El-Kom, Menoufia University

Abstract

In this research, the therapeutic effects of marjoram and vitex agnus-castus were studied, and the biological, biochemical, and histological changes on the ovaries of female laboratory mice were studied. Thirty mice weighing approximately 150 grams ±10 were used during the experiment and were 3 months old. Dried marjoram and vitex agnus-castus concentrates were used at 5% and 10% of the base meal. Mice were fed the basal diet for 5 consecutive days to achieve adaptation. The mice were then divided into 6 groups of 30 mice, each group consisting of 5 mice. After conducting the experiment and recording the results, the estrogen percentage for the negative control group (Group 1) recorded (-) the lowest value compared to the rest of the groups, with a significant difference. The value was 4.56%, while the value reached 4.56%. The group of rats that were fed (2.5%, 2.5%) recorded the highest estrogen value. While the lowest value was recorded with the group fed with 5% vitex agnus-castus compared to the first group (-), with a significant difference, as the values reached (5.3, 16.06), respectively. While the lowest value was recorded with the group fed with marjoram, 10% compared to the first group (-), with a significant difference, as the values reached (7.58, 6.21), respectively. . The histological results confirmed the validity of the chemical analyzes on the reproductive system organs (ovaries, ovarian ducts, uterine wall).

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Journal of Home Economics - Menofia University

Articles in Press, Accepted Manuscript
Available Online from 31 May 2024

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