Document Type : Original research articles
Authors
1
Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University, Shebin El-Kom, Egypt
2
Department of Nutrition and Food Sciences,Faculty of Home Economic, Menoufia University, Shibin El-kom, Egypt
3
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
Abstract
This study aims to determine the effect of kale (Brassica oleracea var. acephala) plant powder and extract used for hyperglycemic rats. Thirty adult male albino rats weighing 150 ± 10 g were used during the experiment. Rats were divided into two main groups. The first main group (5 rats) was fed the basal diet (B.D.) as the control negative group. The second main group (25 rats) was injected with alloxan (150 mg/kg body weight) to cause hyperglycemia and then divided into 5 groups (n=5). The first of these groups was left as a positive control group, while the third and fourth groups were fed on B.D. and administered with ethanolic kale leaf extract (200 and 400 mg/kg body weight) orally, respectively. The fifth and sixth diabetic rats groups fed on kale leaves powder (2.5 and 5% of basal diet), respectively. At the end of the experiment (28 days), blood samples were collected for chemical analysis, and liver and kidneys were extracted for histopathological analysis. Results showed that treating kale leaves in powder or extract reduced serum glucose, TC., TG., LDLc, VLDLc, Liver, Kidney, and MDA. At the same time, the results showed an increase in the levels of HDLc and antioxidant enzymes such as catalase and superoxide dismutase. Biological estimates, such as F.I., FER, and BWG, have also improved. In conclusion, the group treated with 2.5% kale powder achieved the best results, and it is recommended for use in our diets to treat diabetes and its associated complications.
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