Document Type : Original research articles
Authors
1
Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University Shibin El Kom, Egypt
2
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
3
Nutrition and Food Sciences, Faculty of Home Economics, Menofeya University, Egypt
Abstract
The Ginkgo biloba extract (GBE) has been reported to have a wide range of health benefits, this study aims to study Biological and Nutritional Benefit of Capsules and Aqueous Extract of Ginkgo Biloba Herb on Rats with High Diabetes. forty rats weighing (140-160g) were divided into two main groups: The first group (n=5 rats) served as a positive control group, second group (n=35 rats) was injected with alloxan (150 mg/kg B.W), then divided into seven groups (5 rats each), one of them kept as a positive control group, the three left groups were given orally three doses (100-200 & 300 mg/kg B.W) of GBE, respectively. The other two groups were given orally 2 doses (4.68 and 9.36 mg/day) of Capsules, the last group was given the mixture. The obtained result showed that treating rats with GBE, capsules and the mixture, showed a significant decreased (p≤0.05) in the level of serum glucose, LDL, VLDL, ALP, AST and ALT. and significant increase (p≤0.05) in HDL, Insulin, BWG, FI and FER. This study, found that GBE, Capsules and the mixture, had significantly improved hyperglycemia, but it should be noted that high dose of GBE (300 mg/kg B.W) showed very slight effect in reducing blood sugar, the best result was recorded for G4 at a dose (200 mg/kg B.W of GBE). While the capsules showed the best results in reducing blood sugar. In particular, dose (9.36 mg/day) for G7 the mean value was 132.61±3.91 (mg/dl).
Keywords
Main Subjects
)
مشاهدة على SCiNiTO