Document Type : Original research articles
Authors
1
Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University Shibin El Kom, Egypt
2
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
Abstract
Ginkgo extract (GE) has been notified of various health benefits. This study aims to study the biological and nutritional benefits of capsules and aqueous extracts of the Ginkgo herb on rats with high diabetes. Forty rats weighing (10±150g) were separated into two primary groups: the initial group(n=five rats) served as a positive control group, the second group (n=35 rats) was injected with alloxan (150 mg/kg BW), then separated into seven groups (5 rats each), one of them kept as a positive control group, The three groups on the left received orally three doses (100-200 & 300 mg/kg BW) of GE, respectively. The other two groups were given orally 2 doses (4.68 and 9.36 mg/day) of capsules, while the last group was given the mixture. At the end of the experiment, glucose levels, insulin, AST, ALT, ALP, and lipid profile (TG- TC-VLDL-LDL and HDL) were assessed. The obtained result showed that treating rats with GBE, capsules, and the mixture demonstrated a significant decrease in the level of serum glucose, VLDL, LDL, ALP, AST, and ALT. and significant increases (p≤0.05) in HDL, Insulin, BWG, FI, and FER. The capsules showed the best results in reducing blood sugar, followed by the mixture.
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