Document Type : Original research articles
Authors
1
Nutrition & Food Science Dept., Faculty of Home Economics, Menoufia University, Shebin El Kom
2
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
3
Department of Nutrition and Food Sciences,Faculty of Home Economic, Menoufia University, Shibin El-kom, Egypt
Abstract
This research aims to estimate the chemical composition and phenolic compounds of Muskmelon (Cucumis melo L.) powder and evaluate the hyperglycemia effect of it in male albino rats injected with alloxan. Thirty adult male Sprague-Dawley rats were divided into five groups: Group (1): Normal rats or negative control group (-) fed on the basic diet only. Group (2): Hyperglycemic rats untreated group or positive control group (+) fed on the basic diet only, while the groups (3, 4, 5) were hyperglycemic rats and treated with feding on the basic diet with different levels of Muskmelon (Cucumis melo L.) powder (2.5%, 5%, 7.5%), respectively. At the end of the experiment after 28 days, blood biochemical tests were estimated for :( Glucose, TG, HDL-c, LDL-c, VLDL-c, ALT, AST, ALP, urea, uric acid and createnine). The weights of rats and the internal organs were also calculated, in addition to the histopathological examination of the liver and kidneys. The results in hyperglycemia untreated group showed a decrease in weight gain, internal organs and HDL, while an increase in the serum of blood glucose, TG, LDL, VLDL, ALT, AST, ALP , urea, uric acid and createnine. The results improved gradually using Cucumis melo L. powder (2.5%, 5%, 7.5%), respectively and the best group was (7.5%). The histopathological examination of the liver and kidneys also showed in ndesicable pathological histological changes in group (2) "positive control group (+)",
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