Improvement of Male Rats Fertility and Immunity using Nettle Root

Document Type : Original research articles

Authors

Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt.

Abstract

This investigation attempted to examine how nettle root powder affected infertile rats. Twenty-four male rats have been employed, averaging 140-150 grams. Four major groupings have been set up for the animals. To induce male rats to become infertile, the second major group (n=6) was once given injections of cadmium chloride, while the first significant group (n=6) was kept as a negative control group. For 28 days, a 5% nettle root in powdered form diet used to be obtained for one group of infertile rats, even as a third infertile group of rats once received a 2.5% nettle root powder diet. Rats were sacrificed after starving for the duration of the experiment, and blood was once taken and processed to extract the serum. The following measurements have been made: the hormones recognized as luteinizing hormone (LH), follicle-stimulating hormone, additionally recognized as (FSH), and testosterone hormone, different immunological markers that are IgG as well as IgM ranges, liver enzymes, renal functions, lipid fractions like TC, TG, LDL-c, VLDL-c, and HDL-c are some of the lipoproteins that make up the human body, serum glucose, renal biomarkers like uric acid, urea, creatinine and liver enzymes that is ALP, ALT, and AST, have been assessed. The obtained records confirmed that nettle root treatment significantly increased two hormones (Testosterone and FSH). In contrast, LH hormone declined, while glucose, lipid fractions, renal, and liver biomarkers decreased, whilst HDL-c performed the reverse. In conclusion, nettle powder has favorable effects on fertility hormones and the immune system in rats

Keywords

Main Subjects