Document Type : Original research articles
Authors
1
Dept. Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
2
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Egypt
Abstract
This study aimed to investigate the possible hyperlipidemic effect of Argel (Solensromma Argel) leaves powder in adult male albino rats. Thirty-six adult male albino rats weighing 160 ± 10 g were divided into six equal groups (n=6). The first group was kept as a control negative (-ve) group (fed basal diet). The second group was a positive (+ve) control group fed a lipid-rich diet without Argel supplementation. In contrast, the other groups were fed a basal diet supplemented with 1.5% cholesterol and 10% animal fat for 30 days for hyperlipidemia induction. Argel leaves powder was added at 1%, 2%, 3%, and 4% to the diet for groups G3, G4, G5, and G6, respectively. The feeding course was extended for 28 consecutive days. Body weight gain, feed intake, feed efficiency ratio, serum lipid profile (TG, TC, HDL-c, LDL-c, and VLDL-c), serum liver activity enzymes (ALT, AST, and ALP), and kidney function enzymes (creatinine, uric acid, and urea levels) were evaluated at the end of the experiment. The obtained results concluded that feeding on a diet containing Argel leaves powder caused a significant (P≤0.05) increase in HDL-c and a significant (P≤0.05) decrease in body weight gain, blood lipid profile, kidney functions, and liver enzymes. According to the results, Argel leaves powder could successfully treat hyperlipidemia associated with lipid-rich diet intake.
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