Protective Effects of Apricot and Avocado Kernels Powder in Carbon Tetra Chloride-Induced Liver Disorder in Rats

Document Type : Original research articles

Authors

Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt.

Abstract

The goal of the current research was to determine how apricot, avocado kernels, and their combined powder may influence the liver disorder rats. In this research, forty-eight grownup male albino rats have been used in this research, weighting (150±10g) were used and divided into 8 groups, 6 rats each. One of this group was used as a negative control group and the other seven groups injected with carbon tetrachloride (CCl4) to cause liver disorders. The other six groups received apricot, avocado kernels, and a combination of the two at concentrations of 2.5% and 5% from the main diet, while one remained as a positive control group. When the experiment ended, serum lipid fractions consisting of triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL-c), very low-density lipoprotein (VLDL-c), and high-density lipoprotein (HDL-c) levels, serum glucose, liver enzyme activities such as ALP, AST, and ALT, and renal function including uric acid, creatinine, and urea which were examined. From obtained results it could be observed that the best values for protection, improvement of liver functions, lipid profiles, renal functions, and glucose levels were reported at 5.0% mix of apricot and avocado kernels powder. So, it could be concluded that apricot, avocado, and their mixture kernels powder in our regular dishes, that demonstrates the potent nutraceutical therapeutic advantages of consuming apricot, avocado kernels, and both separately and together for curing liver disorder. 

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