Efficacy of Psyllium Husk and Quinoa Seeds on Obese Rat Weight Loss

Document Type : Original research articles

Authors

1 Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt.

2 Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt

Abstract

The goal of the current study was to assess the influence of psyllium husk and quinoa seeds for weight loss in obese rats. Forty male Sprague-Dawley white male rats weighing 140-150g were consisted of 8 groups at random. Five rats used as a negative control group received just a standard diet. They were fed high fat diet could led to obesity, one group of these rats have been defined as a positive control group, and other six groups of rats received treatment with 5, 10, and a combination of both quinoa seeds, psyllium husks. The experimental duration used to be 28 days. Research also measured glucose levels, serum lipid fractions such as whole cholesterol, triglycerides, High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), Very Low-Density Lipoprotein (VLDL), Atherogenic Index (AI), some liver activities that is glutamic oxaloacetic transaminase (GOT) & glutamic pyruvic transaminase (GPT), and renal functions like uric acid, urea, and creatinine. The outcomes that were obtained showed that the plant under examination decreased blood sugar, liver activities, and renal biomarkers, serum LDL-c, VLDL-c and the reverse with HDL-cholesterol in contrast to the positive control group. In summary, overweight rats have been given a 10% psyllium husk and quinoa seed powder combination exhibited most effective lipid fractions, liver activities, renal biomarkers, and sugar ranges, which, in addition to its many health advantages, could be applied in our daily meals and bakery items.

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