Potential Effect of some Bakery Products Supplemented with Spirulina Algae in Alloxan-Induced Diabetic Rats

Khafagy, Mai; El-Shekheby, Hager; El-Kholie, Emad

doi:10.21608/mkas.2023.187551.1207

Potential Effect of some Bakery Products Supplemented with Spirulina Algae in Alloxan-Induced Diabetic Rats

Document Type : Original research articles

Authors

¹ Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt

² Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt.

10.21608/mkas.2023.187551.1207

Abstract

Spirulina has been used to treat some diabetic symptoms because it contains natural antioxidants that can prevent diabetes-related damage to cell function. The research investigates how some bakery products, such as pizza and chocolate cake, include different concentrations of spirulina (2.5 and 5%) and affect diabetic rats. Thirty-six adult albino male rats Sprague –Dawley weighing 140±10 g. Six rats served as the control negative (-ve) group, and thirty rats were injected with alloxan (150 mg/kg/BWt i.p) to induce diabetes. Then, rats were reclassified into the control positive group and four treated rat groups which were administered pizza containing 2.5 & 5% Spirulina and chocolate cake containing 2.5& 5% Spirulina. The treatment period was designed for twenty-eight days. The levels of serum glucose, the liver enzymes [alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP)], the lipid profiles of triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL-c), very low-density lipoprotein (VLDL-c), and high-density lipoprotein (HDL-c), as well as a renal function such as uric acid, creatinine, and urea all were measured. The results revealed that consuming pizza and chocolate cake incorporated with spirulina significantly decreased (P≤0.05) the level of serum glucose of rats, elevated HDL-c significantly, and enhanced liver and kidney functions in treated rat groups compared to the positive control group. In conclusion, adding spirulina-incorporated cake and pizza to our snack diet will significantly lower serum glucose levels.

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