Potential Effects of Ungerminated, and Germinated Quinoa Seeds (Chenopodium quinoa, W.) on Hypercholesterolemic Rats

Document Type : Original research articles

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Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt.

Abstract

Several diseases in humans may have hypercholesterolemia as a precursor. Quinoa is a nutritional food with several properties that lower the risk of developing chronic diseases. This study aimed to determine how different doses of 5% and 10% powdered ungerminated and germinated quinoa affected hypercholesterolemic male albino rats. Thirty-six male albino rats weighing 140g±10g were divided into six groups, one of which was the negative control group (-ve). At the same time, the other five were given Triton-X-100 (100 mg/kg of the rat's weight b.w.) to cause hypercholesterolemia. The following analysis has measured blood glucose, renal functions (urea, uric acid, and creatinine), liver enzymes (alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP), and lipid profile (total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL-c), low-density lipoprotein (LDL-c), very low-density lipoprotein (LDL-c) and atherogenic index (AI). According to the results, both ungerminated and germinated quinoa significantly improved in all biochemical parameters, including lipid profile. The most effective result was for 10% germinated quinoa. In conclusion, quinoa that has been germinated may be a potent nutraceutical therapeutic option for the treatment of hypercholesterolemic rats.

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