The Effect of Arabic Gum and High-Fat Diets on Obese Rats

Document Type : Original research articles

Authors

1 Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University Shibin El Kom, Egypt

2 Nutrition and Food Sciences, Faculty of Home Economics, Menofeya University, Shebin El-Kom, Egypt

Abstract

Obesity is now recognized as a chronic or non-communicable disease. Overweight obesity is a process characterized by excessive accumulation of body fat with multiple organ-specific consequences that could impair health. This study was conducted to study the effect of Arabic Gum and a drug with a high-fat diet on obese rats. Twenty-five obese male rats were divided into five groups: The first group was fed a high-fat diet (G1). The second group was fed 50% Gum Arabic, 15% protein, and 35% fat (G2). The third group was fed 45% Gum Arabic, 15% protein, and 40% fat (G3). The fourth group was fed 40% Gum Arabic, 15%protein, and 45% fat (G4), and the last group was fed on basal diet+ Chitogree (G5). At the end of the experiment (28 days), the rats were sacrificed; the serum was analyzed for liver enzyme, kidney functions, antioxidant status, and lipid profile. The results showed that group 3(40% AG) with a high-fat diet was highly significant (P≤0.05) in losing weight compared with the control group. The lower AST and ALT liver enzyme of a group recorded for group 1(50% AG) with a high-fat diet. Group 4 (Basil diet + drug) was the lowest value in urea, while it was highly significant (P≤0.05) with uric acid values. The lowest values in lipid level were in group 1 (50% AG) compared with the positive control group, while it significantly increased with antioxidant values.

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