Potential Effect of Red Pitaya Fruit on Alloxan Induced Diabetic Rats

Document Type : Original research articles

Authors

1 Nutrition and Food Science Dept., Faculty of Home Economics, Menoufia University, Egypt.

2 Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University.

3 Faculty of Home Economics, Menoufia University

Abstract

This study aimed to discover pitaya fruit's potential health effects on alloxan-induced diabetic rats. Thirty mature albino rats (140-160 g) were divided into two main groups. The first group (n=5 rats) served as a negative control; the second group (n=25 rats) was injected with alloxan to induce diabetes, then divided into five groups (5 rats each), one of them kept as a positive control group. At the same time, the four left groups were given pitaya flesh juice 5 mg/kg BW., pitaya flesh juice 7.5 mg/kg BW., pitaya peels powder 2.5%, and pitaya peels powder 5%, respectively. The treatment lasted for 28 days. According to the findings, pitaya peel powder of 5 percent reduced serum glucose by 201.52 ±3.01 to 105.46 ±1.33 mg/dl in diabetes mellitus. Pitaya peels powder 5% recorded the highest effects in improving kidney parameters, liver enzymes, lipids profile, and antioxidant enzymes. The results suggested that pitaya flesh juice (5 mg/kg. BW ), pitaya flesh juice (7.5 mg/kg. BW ), pitaya peels powder (2.5%), and pitaya peels powder (5%) might be utilized to improve the health status of diabetes mellitus. According to the findings of this study, pitaya fruit is not only beneficial to the health of diabetic people, but it may also be beneficial to individuals with cardiovascular disease and liver and kidney disease. Pitaya fruit improved the biochemical indicators of diabetic rats and lowered Serum glucose. Therefore it can be considered an important dietary intervention method for diabetics.

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