Document Type : Original research articles
Authors
1
Nutrition and Food Sciences, Faculty of Home Economics, Menofeya University, Shebin El-Kom, Egypt
2
Faculty of Home Economics, Shebin El-Kom, Menoufia University
3
Dept. Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
Abstract
The present study was designed to study the effect of chia seeds powder on hepatic rats. Thirty-six adult male albino rats were used in this study; weighting (150±10g) was divided into six groups, six rats each. One of them was kept as a control –ve group, while the other five groups were injected with 1.5% cholesterol for 21 days to induce hypercholesterolemia disorder. One of them was kept as a control (+) group, and the other four groups were treated with chia seeds powder at concentrations of 1.5%, 3%, 4.5%, and 6% from the main diet. Body weight gain, feed intake, feed efficiency ratio, serum lipid profiles (TG, TC, LDL-c, VLDL-c, and HDL-c), serum glucose, serum liver enzymes (ALT, AST, and ALP), and kidney functions (creatinine, uric acid, and urea levels) were determined. From the obtained results, it could be concluded that feeding on chia seeds powder caused a significant (P≤0.05) increase in HDL-c, but with significant (P≤0.05) decreases in body weight gain, liver functions, kidney functions, lipid profile, and serum glucose as compared with control (+ve) group, which reflects the powerful nutraceutical therapeutic effect for feeding on chia seeds powder for treatment hypercholesterolemia disorder in rats. The best results recorded for 6% chia seeds powder
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