Document Type : Original research articles
Authors
1
Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt
2
Nutrition and Food Science Department, Faculty of Home Economics, Menoufia University
Abstract
The present study was designed to study the effect of propolis and beeswax powder on hepatic rats. Forty-eight adult male albino rats were used in this study; their weighting was (150±10g) divided into eight groups, sex rats each. One of them was kept as a positive control –ve group, while the other seven groups were injected with Carbon Tetrachloride (CCl4) to induce liver disorder. One of them was kept as a control (+) group, and the other six groups were treated with propolis, beeswax, and a mixture of them at concentrations of 2.5% and 5% from the main diet. Serum lipid profiles [total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL-c), very low-density lipoprotein (VLDL-c), high-density lipoprotein (HDL-c)], glucose levels, catalase (CAT) enzyme, superoxide dismutase (SOD) enzyme, liver enzyme activities (ALT, AST, and ALP), and kidney functions (creatinine, uric acid, and urea levels) were measured at the end of the experiment. From the obtained results, it could be concluded that feeding rats on propolis and beeswax at a 5% level caused a significant (P≤0.05) increase in HDL-c, catalase (CAT), and superoxide dismutase (SOD) enzymes, but with significant (P≤0.05) decreases in liver functions, kidney functions, lipid profile, serum glucose, and malonaldehyde enzyme as compared with control (+ve) group, which reflects the powerful nutraceutical therapeutic effect for feeding on propolis and bees wax for improving the biochemical parameters which detected in liver illnesses.
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