Document Type : Original research articles
Authors
1
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt.
2
Nutrition & Food Science Dept., Faculty of Home Economics, Menoufia Univ., Egypt
3
Department of Nutrition and Food Sciences, Faculty of Home Economics , Menoufia University,Shibin El Kom, Egypt
4
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
Abstract
The goal of this study was to investigate how different concentrations (2.5 and 5%) of stevia (Stevia rebaudiana) and samwa (Cleome droserifolia) leaves products affected alloxan-induced diabetes complications in rats. Fifty male albino rats weighing 140±10 g were used in this study and divided into two main groups. The first group (5 rats) was kept as a negative (-ve) control group fed on the basal diet. In comparison, the second group (45 rats) was given alloxan (dose 150 mg/kg BW) to induce diabetes and divided into nine equal sub-groups (5 rats per each) as follows: subgroup (1) served as a positive (+ve) control group that was fed on a basal diet, while subgroups (2, 3, 4, 5) diabetic groups were fed on a basal diet and 2.5, 5% of biscuits and cake that were incorporated with stevia leaves products, respectively. While subgroups (6, 7, 8, 9) diabetic groups were fed on a basal diet, 2.5 and 5% of biscuits and cake were incorporated with samwa leaves, respectively. Blood glucose, liver enzymes, lipid profile, and kidney functions were determined. The results revealed that the blood glucose, liver enzymes, kidney functions, and lipid profile significantly decreased (P≤0.05) compared to the positive control group. In contrast, HDL-c level and insulin excretion were significantly improved. So, it could be concluded that adding tested products enhanced the biochemical parameters of diabetic rats.
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