Document Type : Original research articles
Authors
1
Department of Nutrition and Food Sciences,Faculty of Home Economic, Menoufia University, Shibin El-kom, Egypt
2
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
3
Department of Nutrition and Sood Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
Abstract
This search aimed to study the effects of Carthamus tinctorius on rats inflicted with infertility. Thirty male Sprague Dawley rats weighing 160-170 g were used in this study. The animals were divided into six main groups. The first main group (n=5) was kept as a negative control group (-ve), and the second group was (n=5) injected with cadmium chloride to induce infertility in male rats. In contrast, the third infertile group was fed on a diet containing 2% safflower seeds powder, 4th group of infertile rats fed on a diet containing 5% safflower seeds powder, 5th group of infertile rats was fed on a diet containing 7% safflower seeds powder while 6th group infertile rats fed on a diet containing 10% safflower seeds powder for 28 days. At the end of the experiment, rats were fasted overnight before sacrificing, and blood was collected and then centrifuged to separate the serum. Serum glucose, liver functions, kidney functions, lipid profile, testosterone hormone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) were determined. The obtained results revealed that treated groups with safflower seeds led to a significant increase of two hormones (Testosterone, FSH) while LH reduced Serum glucose, cholesterol, triglycerides, LDL-c, VLDL-c, uric acid, urea, creatinine, ALP, ALT, AST decreased, and HDL-c increased.
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