Hypoglycemic Effect of Ropes Roots (Rehium Ribes) and Lemongrass Leaves (Cymbopogon Cittates) in Alloxan-Induced Diabetic Rats

Document Type : Original research articles

Authors

Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt.

Abstract

Lemongrass and Rheum species are medicinal plants commonly consumed as a beverage for health and as a diabetes mellitus (DM) treatment in many countries. The primary purpose of this study was to study the effect of lemongrass leaves, ropes roots, and their mixture powder in lowering hyperglycemia in diabetic rats. Forty male albino rats weighing 140g±5g were divided into eight groups, each with five rats. Rats were given alloxan (150 mg/kg BWT) to make them diabetic. Glucose levels, total cholesterol, triglycerides, high-density lipoprotein (HDL-c), low-density lipoprotein (LDL-c), very low-density lipoprotein (VLDL-c), liver functions (ALT, AST, and ALP), and kidney functions (urea, uric acid, and creatinine) were also assessed. Results showed that the diabetic group had lower glucose levels and improved liver and kidney functions when fed a 5% combination, with significant differences (P≤0.05). Mixture plants had significantly lowest (P≤0.05) cholesterol and triglyceride levels and the lowest LDL-c and VLDL-c values. The group fed 5% mixed plants had the greatest amounts of HDL-c. The group fed 2.5 percent lemongrass had the lowest levels, with a significant difference (P≤0.05). In conclusion, diabetic rats given a 5% mixed powder showed significantly lower glucose levels and studied biochemical tests. Ropes, lemongrass powder, and their mixture could be utilized in our beverages, in addition to the other health benefits.

Keywords

Main Subjects

Files

Share

How to cite

Statistics