Study of the Potential Impact of Atriplex Halimus L. (Chenopodiaceae) on Experimental Animals Infected with Hyperglycemia

Document Type : Original research articles

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1 Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shebin El-Kom, Egypt

2 Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University Shibin El Kom, Egypt

Abstract

The present study aimed to determine the potential effect of Atriplex halimus leaves powder on blood glucose levels in hyperglycemic rats. Thirty adult male albino rats weighing (150±5g) were divided into five groups as follows: Group 1: Negative control group (6 rats) fed on a basal diet, and experimental group (24 rats). The experimental group was infected by alloxan (dose 150 mg per kg) to induce diabetes. Then was divided into four subgroups (6 for each) as follow; positive control group fed on a basal diet, groups (3, 4, 5) diabetic groups were fed on the basal diet, and 2.5, 5, 7.5 % of A. halimus leaves powder respectively for 28 days. Results showed that glucose level in the negative control group was significantly decreased compared with diabetic groups. Blood glucose values were decreased while insulin and BWG were increased with an increase in the percentage of A. halimus leaves powder to the basal diet. The leaves of A. halimus improved the liver and kidney functions; the best and lowest values of creatinine were recorded with groups fed on 7.5% of A. halimus leaves powder compared with the positive control group.

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