Effect of Mulberry, Marshmallow and Psyllium Leaves in Biological and Biochemical Changes on Hyperglycemic Rats

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The effect of 5% mulberry (Morus alba), marshmallow (Althaea officinalis and psyllium (Plantago ovata) leaves powderin biological and biochemical changes on hyperglycemic rats were evaluated. Diabetic rats induced by injection with alloxan (150 mg/kg of rat’s body weight). The results showed that group fed on 5% herbal mixtures showed the highest values of body weight gain, food intake and food efficiency ratio compared with other groups. The highest reduction with significant difference in glucose, alkaline phosphate and glutamic oxaloacetate transaminase (GOT) levels showed with group fed on 5% of mixtures herbals with values 109.1± 0.40mg/dl, 90± 0.80 µ/l and 17.21± 0.90 µ/l, VS 197± 0.90 and 55.82± 1.35, µ/l respectively. A markedly reduction in glutamic pyruvate transaminase (GPT) levels by different rates in hyperglycemic rats fed on different herbs and its mixtures was observed. Group fed on 5% herbal mixtures showed the highest reduction with significant difference in serum triglycerides (TG) and total cholesterol values compared with other tested groups. The maximum reduction with significant difference in HDL, LDL and VLDLc values recorded with group fed on 5% herbal mixtures

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