Document Type : Original research articles
Authors
1
nutrition and food science,faculty of home economic,menofia university,shibin elkom, egypt
2
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menofia University, Shibin Elkom, Egypt
3
Department of Nutrition and Food Sciences - Faculty of Home Economics - Menofiya University - Shebin El-Kom - Egypt
Abstract
This study aimed to compare the effect of mesotherapy and a nutritional mixture (coffee, soybean, and oats) on blood lipids among obese rats. Thirty-six male albino rats, divided into two main groups; 1st group (140±10g), used as a negative control group and kept on a standard diet along with the trial, while the second group (30 rats) were weighing (230±10g), fed on a high-fat diet (20% fat) for 21 days, then divided into five groups (6 rats in each). The first was the positive control group; the second fed 2% of the nutritional mixture; the third fed 4 % nutritional mixture; the fourth was injected with 2.5 ml mesotherapy; and the fifth was injected with 5 ml mesotherapy. The nutritional mixture was made from coffee, soybean, and oats, then dried and administered as powder, while mesotherapy was administered by daily injection. At the end of the experiment, total serum cholesterol (T.C.), triglycerides (T.G.), HDL, VLDL, and LDL were determined. The results showed that positive control rats had higher LDL, VLDL, T.G., and T.C. than the negative control group and other groups. In parallel, the HDL value of the negative control group was significantly the highest. Rats fed 4% of the natural products were more effective in reducing LDL, T.G., and T.C. than rats fed 2% of natural products. Injection with 5% of mesotherapy was more effective in reducing LDL, VLDL, A.I., T.G., and T.C. In conclusion, injection with 5 ml mesotherapy and feeding 4% natural products showed hypolipidemic effects among experimental animals.
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