Document Type : Original research articles
Authors
1
Departement of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University
2
Department of Nutrition and Food Sciences,Faculty of Home Economic, Menoufia University, Shibin El-kom, Egypt
3
Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt
4
Faculty of Home Economics, Menoufia University.
Abstract
The objective of this study was to reduce obesity in rats fed a high-fat diet using citron melon plant parts. Fifty (50) male albino rats (Sprague- Dawley strain) (140±10g each) were used and divided into two main groups. The first main group (5 rats): negative control fed on a standard diet along with the experiment and the second main group (45 rats) (225 ± 20g), fed on a high-fat diet (10% cheap fat for 21 days to induce obesity) then were divided randomly into nine subgroups (5 rats each). Subgroup 1:positive control fed on a standard diet, subgroups 2,3, 4, 5, 6, 7, 8 & 9 were fed on a standard diet containing 2.5, 5% citron melon pulp (juice), 2.5, 5% citron melon seeds powder, 2.5, 5% citron melon peels powder, 2.5 and 5% mix of all parts (juice + powder), respectively. At the end of the experiment 28 days, the rats were sacrificed and blood samples were collected for analysis. In comparison with other experimental groups, the results indicated that diet 5% citron melon peels significantly decreased bodyweight, T.C, T.G, LDL, VLDL, AI, and blood glucose (P ≤ 0.05), while diet 5% citron melon pulp revealed the highest increase in serum HDL level (P ≤ 0.05) compared with control positive group. In conclusion, citron melon peels were effective in reducing body weight among obese rats, and they may be a promising supplement for bodyweight reduction.
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