Nutritional and Biochemical Studies of Annona (Annona Squamosa) and Lemon (Citrus Aurantifolia) Leaves Powder on Hyperlipidemic Rats

Document Type : Original research articles

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Departement of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt

Abstract

This study was carried out on the effect of nutrition and biochemical of Annona and lemon leaves powder on hyperlipidemic rats. The present study was designed to determine the effect of both Annona and lemon leaves powder on hyperlipidemic rats. Forty adult albino rats Sprague –Dawley strain weighing 120 ±10 g was randomly classified into eight groups. Five rats served as a negative control group that fed on basal diet only while the other 35 rats were fed by10% animal fat. Rats were randomly into a positive control group, six treated rat groups that were fed on 2.5%,5%, and 7.5% of Annona and lemon leaves powder. The study period was 28 days. Phenolic compounds of Annona and lemon leaves were determined using the HPLC technique. The results of the obtained data indicated that the treated groups (hyperlipidemic rats) resulted in decreased TC, TG, LDL& VLDL in the blood and increased HDL compared with a positive control group with significant difference (P≤0.05). Also, the results indicated that the treated groups resulted in increased oxidative enzymes (CAT, SOD& GSH) compared with a positive control group with significant difference (P≤0.05). Also, the obtained results indicated that the treated groups showed a decrease in (AST, ALT& ALP) compared with a positive control group with a significant difference (P≤0.05).  The result of phenolic compounds of Annona and lemon leaves revealed that each leaf contains high amounts of phenolic compounds, and it can use as an antioxidant. The study clearly demonstrated that rats fed on Annona and lemon leaves powder could ameliorate hyperlipidemia in rats.

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