Document Type : Original research articles
Authors
1
Dept. Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin El Kom, Egypt
2
Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University, Shebin El-Kom, Egypt.
3
Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University.
Abstract
The present study aimed to investigate the effect of Khella Baladi on the amelioration of kidney dysfunction in hyperoxaluric rats. Thirty-six adult male albino rats were divided into six groups, six rats for each. One of them was kept as a (–ve) control group, while the other five groups were treated with ethylene glycol 0.75% and ammonium chloride 1% for a week via the drinking water to induce hyperoxaluria. Khella Baladi was added to five groups in different quantities (1.5, 3, 4.5, and 6%), respectively. The treatment lasted for 28 days. From the obtained results it was showed that treatment with Khella Baladi in different quantities (1.5, 3, 4.5, and 6%), respectively for 28 days caused a significant (P ≤ 0.05) increase in weight gain%, feed intake, feed efficiency ratio, HDLc, total protein, albumin, globulin, and serum (Na & K), but with significant (P ≤ 0.05) decrease in relative organs weights, liver functions, kidney functions, urine (Na &K), serum glucose, serum bilirubin fractions, TC, TG, LDL, and VLDL. The best treatment was for Khella Baladi 6%. Therefore, it can be concluded that Khella Baladi could minimize the hyperoxaluric effect of (NH4Cl+EG) and potent a diuretic effect.
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