Feeding On Some Selected Food Processing By-Products To Improve The Obesity Disease Complications In Rats

Document Type : Original research articles

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Abstract

The present study aims to investigate the effectiveness of selected food processing by-products mixed in loaves bread in modulating obesity parameters and its complications in obese rats. Forty two (160-170g per each), were divided into two main groups, the first group (Group 1, 6 rats) still fed on basal diet and the other main group (36 rats) was feed with diet-induced obesity (DIO) for 8 weeks which classified into sex sub groups as follow: group (2), fed on DIO as a positive control; groups (3-7), fed on DIO containing 5 % potato peel powder (PPP), cauliflower leaves powder (CLP), red onion skin powder (ROSP), mango peel powder (MPP) and their  mixture, respectively. Feeding of rats on diet induced obesity (DIO) for eight weeks leads to increase the bodyweight (BW) than the control group which recorded 183.27 and 221.50 % of baseline, respectively. Replacement of wheat flour with 5% of PPP, CLP, ROSP, MPP and their mixture induced significant decreasing on BW of the obese rats which recorded 205.47, 210.48, 196.91, 198.61 and 191.09 % of baseline, respectively. Biochemical analysis data indicated that obesity induced a significant increased in blood lipids profiles (TG, 32.52%; TC, 23.04% and LDL, 51.78%) (p≤0.05), liver functions (ALT, 33.65% and AST, 32.54%), kidney functions (uric acid, 33.68% and creatinine, 29.62%) and serum glucose (38.63%) compared to normal controls. Also, some immunological parameters (albumin level and protease activity) in serum of obese rats were significant decreased (p≤0.05). Feeding on 5% of PPP, CLP, ROSP, MPP and their mixture exhibited a significant improvement (p≤0.05) in all of these parameters by different rates. The higher amelioration effects were recorded for the by-product mixtures treatment followed by ROSP, MPP, PPP and CLP, respectively. In conclusion,these findings provide a basis for the use of the selected food processing by-products and also have important implications for the prevention and early treatment of obesity.

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