Effect of Tomato Juice In Lipid Profile and Antioxidant Status in Old Femele Rats

Document Type : Original research articles

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Abstract

Aging is considered to be either “primary,” that is, the inevitable deterioration of cells and tissues structure and function that occurs independent of disease, lifestyle, and environmental causes, or“secondary,” where the decline in tissue structure and function occurs as a result of external influences, including diseases. Chemical constituent, total phenolic, lycopene , β-Carotene and total flavonoids contents were determined in tomato juice. Fed the diet of twenty old female rats administrated different orally levels as tomato juice to improve their lipid profile and antioxidant status. The result showed that after (28)days the level of Glutathione reductase (GSH), catalase(CAT) and Superoxide Dismutase (SOD) in 12 ml tomato juice group were significantly (p < 0.05) increased when compared with the positive control group ,but the mean value of Malondialdehyde (MAD) in 12 ml tomato juice group was lower than that in positive control group. Significant correlations were observed among the levels of serum triglyceride, serum total cholesterol, serum total lipid, high-density lipoprotein (HDL) cholesterol ,atherogenic indices (Atherogenic Coefficient (AC), Cardiac Risk Ratio (CRR) and Atherogenic Index (AI)) .So, it could be concluded that  tomato juice at level 12 ml was partly attributed to the reduced absorption of lipid ,cholesterol and increased antioxidant Parameters.          

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