The Potential Effect of cocoa powder on serum lipids profile and antioxidant status inhypercholesterolemic rats

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Abstract

The present investigation aims to evaluate the effect of cocoa powder on serum lipids profile and antioxidant status in normal and hypercholesterolemic rats. Twenty four adult albino Rats were randomly divided into two main groups. Group I: negative control (6 rats) was fed on standard diet . Group II: hypercholesterolemic groups (18 rats) were divided into equal three sub groups, the first: positive control group, the second and the third groups were fed on  standard diet containing  2.5 and 5% of cocoa powder respectively. The results indicated that  the consumption of cocoa led to decrease the levels of blood cholesterol,LDLc and VLDLc as compared with the positive control group. On the other hand, the treatments significantly p≤0.05 increased the glutathione transferase and catalase level activities compared with the positive control group, while the malonaldehyde content  had the opposite trend. In conclusion, this study indicated that cocoa used effectively in reducing the levels of lipid profile in hypercholesterolemic rats.

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