Therapeutic Effects Of Anti- Diabetic Agents From Medicinal Plants And Seeds On Hyperglycemic Rats

Document Type : Original research articles

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Abstract

Recent global statistics showed a high diabetes incidence which affect millions annually. It has become necessary to use supported methods in the treatment to reduce complications that may resulting from diabetes. Medicinal plants and seeds play an important role in the treatment of diabetes. This study aims to improve the health status reducing complications by using some medicinal plants and seeds (Ocimum sanctum leaves, Psidium guajava leaves, Momordica charantia seeds and Acacia Arabica seeds) individually and as mixture, through studying of biological changes and biochemical and histopathological for diabetic male albino rats, results revealed:
The ninth group fed a mixture of Ocimum sanctum leaves, Psidium guajava leaves, Momordica charantia seeds and Acacia Arabica seeds in dose 4g/kg b/w in ratio (1: 1: 1: 1) achieved the highest drop in blood sugar levels and creatinine and AST and ALP in serum blood, compared to the positive control group. while the fourth set, which fed on a mixture of Momordica charantia seeds and Acacia Arabica seeds achieved in dose 4g/kg b/w in ratio (1: 1) , the largest decline in urea level and lipoprotein low-density LDL in serum blood compared to positive control group. The third group, which fed on the seeds of Momordica charantia seeds in dose 4g/kg b/w, the highest drop in the level of triglycerides recorded trilateral very low and lipoprotein density VLDL and ALT compared to the positive control group. the ninth group fed a mixture of Ocimum sanctum leaves, Psidium guajava leaves, Momordica charantia seeds and Acacia Arabica seeds achieved in dose 4g/kg b/w in ratio (1: 1 : 1: 1) , the highest elevation in the level of high density lipoprotein (HDL) and albumin and globulin compared to the positive control group < /p>
 

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