Anti DiabeticAnd HepatoprotectiveEffect Of Cloves (SyzygiumAromaticum Linn) On Rats Induced By Aloxan

Document Type : Original research articles

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Abstract

This study was conduced to investigate the effect of Syzygiumaromaticumon Diabetic Rats. Thirty six mature albino rats weighting 150-160g each were used, and divided into 6 equal groups, one was kept as a control-ve group, while the other groups were made diabetes by Aloxan (150 mg/kg). The tested plant was given as a percent of 3, 5, 7, and10% from the Basel diet for four weeks. After the treatment, blood samples were taken and serum glucose, triglyceride, total cholesterol, LDL-C, GOT, GPT, and ALP levels were measured, while HDL-C and VLDL- C were calculated. The results indicated that rats treated with Aloxan recorded significantly increasing in serum glucose, total cholesterol, LDL-C, VLDL-C and triglyceride levels (p<0.005) while HDL-C level was decreased (p<0.005) as compared to the control group. Treatment of diabetic rats with Syzygiumaromaticum caused a decrease in serum glucose, total cholesterol, LDL-C, VLDL-C, triglyceride levels, AST, ALT and ALP (p<0.005) with an increase in HDL-C level (p<0.005) when compared with the control group. It could be concluded that Syzygiumaromaticum were effective in protecting against diabetic rats not only decreased the level of serum glucose but also has beneficial effect on serum lipids and liver function. Therefore, we recommended this tested plant by a moderate amount to be included in our daily drinks.

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