Biological Study on the Potential Effects of Bael Fruit (Aeglemarmelos L, Correa)onHypercholestreolemic Rats

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Abstract

The present study was conducted to investigate the potential effects of Baelfruit (Aeglemarmelos L, Correa)powder (BFP) on the biological activities of rats. The experiment was carried out on 30 male Albino rats divided into 5equal groups (6 rats per each);the first group fed on basal diet and kept as a (control-). Rats in the other four groups fed on basal diet containing 1.5% cholesterolplus 0.25% bile salts for two weeks to induce hypercholesterolemia, then those rats were subdivided into the following groups: a group that remained as hypercholesterolemic (control+, secondgroup), a group that fed on hypercholesterolermic diet plus5% BFP(thirdgroup); a group that fed on hypercholesterolemic diet plus7.5% BFP (fourthgroup); a group that fed on hypercholesterolermic dietplus10% BFP (fifthgroup).The results showed that with increasing the amount of BFP or beverage, the total cholesterol, triglycerides, LDL-c, AST, ALT, urea nitrogen and glucose levels decreased significantly (P≤ 0.05)and the best result was belonged tothe group of rats that fed on BFP by 10%. From the obtained results it can be concluded that, supplementation with high percentage of BFP, 10%, exerts a positive impact on the lipid profile and other biochemical parameters in hypercholesterolemic rats.As well as BFP is recommended to be ingested as fresh fruit tohypercholestreolemic patients.

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