Therapeutic Effects of  3 New Plant Formulea Contaning Saffron  As Used For Hyper Cholesterol Nolemia Hepatic Rats .

EL-Dashlouty, Mohamed; Abdel Rahman, Abeer; El-Shehaly, Asmaa

doi:10.21608/mkas.2017.166189

Therapeutic Effects of 3 New Plant Formulea Contaning Saffron As Used For Hyper Cholesterol Nolemia Hepatic Rats .

Document Type : Original research articles

Authors

10.21608/mkas.2017.166189

Abstract

This study was carried out to evaluate the anti hepatic effects ( Leading to Hypercholesterolemia ) of Saffron , Mahlab , black seed , juniper , almond , mango leaves , mugwort , Kidney beans , noasted mature date seeds and clover leaves on rats.Fifty-four male mature albino rats , weighing 150-160g per each, were used in this study and divided into 9 equal groups, the first group was kept as a control – group, while the other groups were induced by CCL4 By 2 ml/k.B.W.T.g towice per week for two weeks to induce hepatic rats. The powders were given to the rats as a percent of 5 and with and without 0.5% saffron from the basel diet for 28 days. At the end of the experiment, serum Total cholesterol (TC), triglycerides (TG) , High density lipoprotein (HDL-c) , Low density lipoprotein (LDL-c) ,Very low density lipoprotein (VLDL-c) , and A.I were calculated.The results of the obtained data indicated that tested plant formulea significantly (P≤0.05) decreased serum TC, TG, LDL, VLDL and A.I while increased HDL Also, the tested plants improved liver histopathological changes. The obtained findings reveuled that saffron enhanced the several compounds that were able to improve the adverse changes in hepatic rats.

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