Study the Effect of Dry Rose Petals (Rosa damascena) Powder on Blood Lipids and Glucose in Experimental Rats

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This study was conduced to investigate the effect of  rose petals  (Rosa damascena) powder (RPP) on blood lipids and glucose in experimental  rats. Fifty-Four a dult male albino rats weighting150±10g, were used, and divided into three main groups ,First group (5 rats) fed on basal diet as control (-),Second group was  induced diabetes by aloxan (150 mg/kg) , third group was induced hyperlipidemia by fed rats on diet containing high lipids( basal diet + 20 % animal fat sheep's tail) for three consecutive weeks . Diabetic and hyperlipidmic rats groups divided into four sub groups, srats per each two of them were  diabetic and hyperlipidimic control positive.While the other groups  fed a basal diet after replacing 1, 2.5 and 5% RPP and feeding continued for 30 days. After the treatment,  body weight, feed intake (FI),(FER) and blood samples were measured  and serum glucose, triglyceride, total cholesterol ,LDL-C, AST, ALT and ALP  levels were determinid, while HDL-C and VLDL-C Were calculatedand Histopathological structure of liver has been evaluated. The obtained results  revealed that feeding on  RPP caused significant (P ≤ 0.05) improvements in weight gain, FI, FER , HDLc, ,but with significant (P ≤ 0.05) decreases in the rest of the parameters as compared with control (+ve) group. Histopathological investigations confirmed the biochemical changes in rats serum  . It could be concluded that rosa petals powder was effective in protecting against diabetic and hyperlipidimic rats not only decreased the level of serum glucose but also has beneficial effect on serum lipids and liver functions .Therefore, we recommended the RPP tested plant by a moderate amount (5%) to be included in our daily drinks and diets

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