Hepatoprotective Effect of Radish (Leaves and Roots) in CCl4 Induced Hepatic rats

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Abstract

Effect of different concentrations 2.5 and 5 % of radish leaves and roots as powderon biological and biochemical changes of hepatic rats was investigated. Sixty three male Albino rats were used and divided to 6 groups, each group (6) rats. The rats treated with carbon tetra chloride (CCl4). Results indicated that the highest ALT liver enzyme of treated groups (hepatic groups) recorded for 2.5 % radish leaves, while the lowest value recorded for 5.0% radish roots with significant differences. The mean values were 133.0 and 87.0 U/L, respectively. The highest GOT and GPT liver enzyme of hepatic groups recorded for 2.5 % radish leaves, while the lowest value recorded for 5.0% radish roots with significant differences. The highest serum triglycerides and serum cholesterol levels of hepatic groups recorded for 2.5% radish leaves, while the lowest value recorded for 5.0 % radish roots with no significant differences. On the other hand, the highest high density lipoprotein cholesterol levels of hepatic groups recorded for 5.0 % radish roots, while the lowest value recorded for 2.5% radish leaves with significant differences. The verse versa recorded for LDL-c and VLDL-c. Also, the highest glucose levels of treated groups (hepatic groups) recorded for 2.5 % radish leaves, while the lowest value recorded for 5.0% radish roots with significant differences. The highest serum urea, uric acid and creatinine levels of hepatic groups recorded for 2.5% radish leaves, while the lowest value recorded for 5.0 % radish roots with significant differences. As conclusion, 5% radish leaves and roots recorded the best levels for hepatoprotective, improvement lipid profile, kidney functions and glucose levels.

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