The Effect Of Feeding With Molokhia  (C. Olitorius) Leaves Powder On Lead Poisoning Rats.

Abd El-Rahman, Abd El-Rahman; Elwi, Yasser; Abd Rabou, Eman; Abd El-Hamed, Eman

doi:10.21608/mkas.2018.165078

The Effect Of Feeding With Molokhia (C. Olitorius) Leaves Powder On Lead Poisoning Rats.

Document Type : Original research articles

Authors

10.21608/mkas.2018.165078

Abstract

Heavy metal poisoning, especially Lead poisoning has harmful effects to human health. Moreover, many searches found that there are some plants have anti-poisoning for metal. Thus, this research was carried out to study the effect of feeding Lead poisoning rats on 5, 10 and 15% molokiha (Corchorus olitorius) leaves powder for eight weeks on blood lead concentration, functions of kidney and liver and histological examination of liver, kidney and brain organs. The results showed that the molokiha leaves powder had high nutritional value; it had high contents of fiber, vitamins and total phenol. Moreover, as a result of feeding poisoning rat on molokiha leaves powder, the group feeding on 15% molokhia had the highest levels of feed intake, body weight gain and feed efficiency ratio compared to the positive control group and other groups feeding on molokiha. Moreover, the results indicated that the levels of blood lead concentration, liver enzymes and kidney function as urea nitrogen, uric acid and creatinine of Lead poisoning rats were decreased as a result of increase the levels of feeding on molokhia leaf powder. So, the group feeding on 15% molokiha had the lowest levels of all these analyses compared to the positive control group and other groups.Furthermore, histological examination of kidney, liver and brain organs of rats showed that the group feeding on molokhia 15% showed that the harmful of Lead poisoning in rats was decreased compared to the positive control group and other feeding groups. However, it was insufficient to treat all changes in these organ tissues as a result of lead poisoning. Finally, the molokiha leave powder had high contents of compounds as fiber, total phenol and vitamins that had high antioxidant activity and antitumor for organ tissues of kidney, liver and brain.So, it can be utilized asan anti-poisoning for Lead poisoning.

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