Effect of some food processing by-products on obesity complications induced in experimental animals

Document Type : Original research articles

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Abstract

The present study aims to investigate the effectiveness of some food processing by-products on obesity complications induced in experimental animals. Thirty male albino rats (150-160g per each), were divided into two main groups, the first group (Group 1, 6 rats) still fed on basal diet and the other main group (25 classified into five sub groups as follow: group (2), fed on DIO as a positive control; groups (3-6), fed on DIO containing 5 % potato peel powder (PPP), yellow onion skin powder (ROSP),eggplant peel powder (EPP) and their  mixture, respectively.Feeding of rats on diet induced obesity (DIO) leads to increase the BW than the control group. At the end of the experiment (8 weeks), rats of the normal group recorded 188.02% of baseline for the BW while obese group was 231.07% of baseline.  Replacement of wheat flour with PPP, YOSP, EPP and their mixture induced significant decreasing on BW of the obese rats which recorded 217.04, 203.03, 209.56 and 193.04% of baseline, respectively.Biochemical analysis data indicated that obesity induced a significant increasein liver functions (AST, 33.88%, ALT, 25.62% and ALP, 26.76%, kidney functions (uric acid, 12.66% and creatinine, 15.69%) and serum glucose (31.54%) compared to normal controls. Feeding on 5% of with PPP, YOSP, EPP and their mixture exhibited a significant improvement (p≤0.05) in all of these parameters by different rates. The higher amelioration effects were recorded for the by-product mixtures treatment followed by YOSP, EPP and PPP, respectively. In conclusion,these findings provide a basis for the use of the selected food processing by-products in different therapeutic nutrition application such as prevention and early treatment of obesity.

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