Effect Of Basil (Ocimum Basilicum) And Thyme (Thymus Vulgaris) Leaves On Biological And Biochemical Changes In Induced Obese Rats

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The present study aimed to evaluate the effect of addition different concentrations (2.5 and 5 %) as powder ofbasil (Ocimum basilicum) and thyme (Thymus vulgaris) leaves and their mixture on biological, biochemical and anti-obesity changes of obese rats. Forty eight adult albino male rats weighting 140 ±10 g were randomly divided into 8 groups (6 rats each) and fed on the basil diet. The first group as a negative control and the other seven groups were adminstrated by high fat diet (20% animal fat) to induce obese rats. Results showed that the highest body weight gain (BWG) and feed efficiency ratio (FER) recorded for (5%) mixtures from thyme and basil leaves powder, while the lowest BWG and feed intake (FI) recorded for (5%) basil leaves powder. The highest feed intake recorded also for (2.5%) thyme leaves powder. The lowest GOT and GPT recorded for (5%) mixtures of thyme and basil leaves with significant difference. The lowest cholesterol and triglyceride recorded for group fed on (5%) mixtures of thyme and basil leaves with significant differences. The highest (HDL-c) levels recorded for group fed on (5%) thyme leaves, while the lowest (LDL-c) recorded for group fed on (2.5%) mixtures of thyme and basil leaves. The lowest (VLDL-c) recorded for group fed on (5%) mixtures of thyme and basil leaves. The lowest uric acid, urea and creatinine recorded for group fed on (5%) mixtures of thyme and basil leaves with significant differences. As conclusion, obese rats treated with (5%) mixtures of thyme and basil leaves had improved lipid profile & liver and kidney functions compared with different level of thyme or basil leaves each alone.

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