Possible Effects of Lotus (Petals & Seeds) in Streptozotocin-Induced Diabetic Rats

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            The present study was designed to compare the effect of different parts of louts (Nelumbo nucifera) (petals and seeds) on diabetic rats. Forty adult male albino rats were used in this study, weighting (140±10g) were divided into eight groups, five rats each. Louts petals, seeds and their mixture as powder were added at percent of 2.5 % and 5% from the basal diet. Rats injected with streptozotocin dose of 40 mg/kg to infect diabetes. Evaluation the chemical composition and nutrient contents of louts such as total phenol, total flavonoids and antioxidant activity. Initial weight, final weight, feed intake (FI), Feed Efficiency Ratio (FER), (BWG %) and relative organs weight, serum glucose, serum lipid profiles (TG, TC, LDL-c, VLDL-c,   HDL-c and AI), serum liver enzymes activities (AST, ALT and ALP) and kidney function (creatinine, uric acid and urea levels) were determined. From the obtained results it was shown that feeding on lotus petals, seeds and their mixture as powder caused significant (P ≤ 0.05) increases in HDL-c, compared with control (+ve) group, and enhanced the kidney and liver functions with the decrease of ALT, AST, ALP, serum glucose, creatinine, uric acid, urea which reflects the powerful nutraceutical therapeutic effect for feeding on lotus petals, seeds and their mixture powders for treatment diabetic in rats. The best result was that of 5% lotus mixture powder diet.

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