Comparative Study of White, Brown and Black RiceEffects on Hypercholesterolemic Rat

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Abstract

This study was carried out to compare white,brown,blackrice, their mixture and biscuits effects on hypercholesterolemic rats.Thirty- fivemale mature albino rats weighing 150-160g per each, were used in this study and divided into 7 equal groups, the first group was kept as a control -ve group, while the other groups were fed on hypercholes -terolemic diet for 3 weeks to induce hypercholesterolemia.The tested plant powdertheir mixtureand biscuitwere given to the rats as a percent of 5 % from the Basel diet for 28 days. At the end of the experiment, serumtotal cholesterol(TC), Triglycerides(TG), High density lipoprotein (HDL-c), GOT, GPT, ALP, urea, creatinine, uric acid were determined. Also,low density lipoprotein(LDL-c), verylow-density lipoprotein (VLDL-c), and (A.I) were calculated .Also, heart was exemminedHis -topathologicaly.The results indicated that tested plants significantly (P≤0.05) decreased serum TC, TG, LDL, VLDL and increased HDL and A.I.Moreover, the tested seeds improved liver and kidney functionsand prevent some of the adverse histopathological changes in liver. The obtained findingshypothesized that tested plant parts containing several compounds which are able to improve the adverse effects and inhibited hypercholesterolemia.So,the data recommended to takewhite,brown, blackrice by a moderate amount in our diets.

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