Study The Effect of Leaves and Fruits of Figs (Ficuscarica, L.) and Olive (Oleaeuropaea, L.) on Obesity and Kidney Disorder Rats

El-Bedewy, Laila; Ali, Mohamed; Abd El-Rahman, Abeer; Said, Seham

doi:10.21608/mkas.2020.160380

Study The Effect of Leaves and Fruits of Figs (Ficuscarica, L.) and Olive (Oleaeuropaea, L.) on Obesity and Kidney Disorder Rats

Document Type : Original research articles

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10.21608/mkas.2020.160380

Abstract

The Effect of leaves and fruitsof figs (Ficuscarica, L.) and olive (Oleaeuropaea, L.) on obesity and kidney disorder rats were studied.Sixty six adult male albino rats of sprague-dawely weighting (150-160g), All rats fed on a basal diet for 7days to make adjustment and then divided into three main groups as the following: The first main group (6 rats) (Group (1)): fed on basal diet as a control negative group,The second main group (30 rats): fed on the high fat diet with saturated fats to induce obesity and then divided to five subgroups each 6 rats,thesefed on high fat diet as a control positivegroup, other groupratsfed on 5% from olive (Oleaeurpaea)leaves, rats fed on 5% from figs (ficuscarica) leaves, rats fed on 5% from olive fruits and ratsfed on 5% from fig fruits.
The third main group (30 rats): rats injected with gentamicin (100mg/kg/day) to induce impaired kidney rats and then divided to subgroups each 6 rats, these rats with impaired kidney fed on basal diet as a control positive group, rats with impaired kidney and fed on 5% fromolive leaves, ratsfed on 5% from fig leaves, rats fed on 5% from olive fruits and ratsfed on 5% fromfigfruits. Administration of leaves and fruits of figs (Ficuscarica L.) and Olive (Oleaeuropaea, L.) on obesity rats at 5% lowered the concentrations of total cholesterol, triglycerides, LDL-c, VLDL-c and decreased of urea, creatinine and uric acid. On the other side, HDL-c was significanlyincreased. Histopathological examination showed amelioration ofhistopathological lesions seen in kidney of kidney disorderrats when received the leaves and fruits of figs (Ficuscarica L.) and Olive (Oleaeuropaea, L.). So, from this study itcan be concluded that intake of fruit and seeds powder of figs (Ficuscarica L.) and Olive (Oleaeuropaea, L.) especially at 5% can be useful for treating obesity and kidney disorder rats.

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