Malnutrition is prevalent among patients with chronic liver disease. Therefore, the aim of this work is to assess the nutritional status of patients with Hepatitis C virus and based therapy of sofosbuvir. Patients were compared with the different methods which used for nutritional assessment namely the anthropometric measures and the Subjective Global Assessment (SGA). Patients and Methods: This study was conducted in Mahalla Hepatology Teaching Hospital in order to assess the nutritional status of 68 chronic hepatitis C patients receiving triple antiviral regimen that consisted of (Sofosbuvir (Sovaldi) + Daklinza + Ribavirin) that were administered orally for 3 months and dual antiviral regimen that consisted of Sofosbuvir (Sovaldi) + Daklinza) that are administerd orally for 3 months with 40 chronic hepatitis C patients per group. Thorough history taking, physical examination and detailed nutritional assessment were performed including a 24- hour dietary recall. Evaluation of nutritional status was done using different anthropometric measures and the Subjective Global Assessment (SGA). Nutritional assessment based on Comparison of dual therapy with triple therapy laboratory findings of those patients that reflect their nutritional status as hemoglobin, liver enzymes (AST, ALT), total bilirubin, ultra sound, WBCs count and platelets count before treatment and after treatment. Results: The study revealed that 73.5% of patients have good nutritional status with SGA score A, 25.0 % of patients have mild to moderate nutritional status with SGA score B, while 1.5% of patients have poor nutritional status with SGA score C. laboratory findings of those patients as follows: Triple antiviral therapy had a more evident impact in their laboratory investigations as decrease in the levels of hemoglobin, white blood cells count, platelets count, Liver enzymes (AST and ALT) and increase in level of total bilirubin than dual antiviral therapy.
Al Shafei, S., Rezk, S., & Badr, S. (2020). Assessment of Nutritional Status of Patients with Hepatitis C in Mahalla Hepatology Teaching Hospital. Journal of Home Economics - Menofia University, 30(4), 351-365. doi: 10.21608/mkas.2020.160376
MLA
Sahar Al Shafei; Samar Rezk; Samira Badr. "Assessment of Nutritional Status of Patients with Hepatitis C in Mahalla Hepatology Teaching Hospital". Journal of Home Economics - Menofia University, 30, 4, 2020, 351-365. doi: 10.21608/mkas.2020.160376
HARVARD
Al Shafei, S., Rezk, S., Badr, S. (2020). 'Assessment of Nutritional Status of Patients with Hepatitis C in Mahalla Hepatology Teaching Hospital', Journal of Home Economics - Menofia University, 30(4), pp. 351-365. doi: 10.21608/mkas.2020.160376
VANCOUVER
Al Shafei, S., Rezk, S., Badr, S. Assessment of Nutritional Status of Patients with Hepatitis C in Mahalla Hepatology Teaching Hospital. Journal of Home Economics - Menofia University, 2020; 30(4): 351-365. doi: 10.21608/mkas.2020.160376
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