Protective Effects of Apricot and Plum Kernel Powder in Carbon Tetra Chloride-Induced Liver Disorder in Rats

Document Type : Original research articles

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Abstract

Effects of different concentrations 2.5 and 5 % of apricot, plum and their mixture as powder on biological and biochemical changes of hepatic rats were investigated. Eighty four male albino rats were used and divided to 8 groups, each group (6) rats. The rats treated with carbon tetra chloride (CCl4). Results indicated that the highest GOT liver enzyme of treated group recorded for group fed on 2.5 % apricot kernel powder but, the lowest value recorded for group fed on 5% mixture apricot and plum with a significant difference at (P≤0.05). The mean values were 71.50 and 53.70 U/L, respectively. The highest GPT liver enzyme of treated group recorded for group fed on 2.5 % plum kernel powder but, the lowest value recorded for group fed on 5% mixture apricot and plum with significant difference at (P≤0.05). The mean values were 16.05 and 11.80 U/L, respectively. The lowest triglyceride and total cholesterol level recorded for group fed on 5% mixture apricot and plum kernel. On the other hand, the highest HDL-c of treated group recorded for group fed on 5% mixture of apricot and plum kernel powder. The verse versa recorded for LDL-c and VLDL-c. Also, the lowest glucose, urea, uric acid and creatinine levels recorded for 5% mixture plum and apricot kernel powder with significant differences. As conclusion, 5.0 % mixture of apricot and plum kernel powder recorded the best levels for protective, improvement lipid profile, kidney functions and glucose levels.  Therefore, apricot and plum kernel powder and their mixture could be used in our beverages and daily dishes

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