Biological , studies of some herbal and plants formula on the healthy status of obese female Rats

The effects of Portulaca, Thyums, Nigella seeds, Origanum, Linum, Elettaria, Rosmary, Zingiber, Cinnamoum, Oat, Pomegranate Peel and Vitellaria Paradoxa on biological, biochemical and histological parameters of obese rats were studied. Thirty-Five adult female albino rats of Sprague- Dawely, weighting (190±5g) and age (3 months). All rat fed on a basal diet for 15 days then rats fed on high caloric diet (contained 25% fat) for 15 consecutive days to induce obesity and rats divided into 7 groups, one group fed on basal diet as control group, while the left six groups were given daily plants and herbal formula at the level 10% (50% plant and 50% tested herbs) for 28 days. Results showed that body weight gain was markedly lower especially in the group 7, lowered concentrations of total cholesterol, triglycerides, LDL-c, VLDL-c and decreased level of AST and ALT enzymes and a in case of HDL-c concentrations were significant increased. Histopathological examination showed amelioration of histopathological lesions seen in liver of obese rats in control group while rats when received the herbs and plants formula helped to increase the accumulation of fat in the liver. So, from this study, it could be concluded that intake of formula of tested herbs and plants powder at 10 % can be useful for improving the body weight and the other parameters for obese female rats and histopathological examination showed amelioration of histopathological lesions seen in liver  of obese rats when received the herbs and plants formula.