Effect of Different Levels of Molina (Lagenariasiceraria)on the Healthy Status of Rats with Anemia

Document Type : Original research articles

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Abstract

The potential health benefits of molinaas functional food supplement to improve iron absorption as well as to prevent and treat anemia  associated with deficiency in iron intake were evaluated in rats. Three experimental groups were fed diet supplemented with different levels of Molina for 4 weeks versus the control rat group fed basal diet free in iron .At the end of the experiment, rat groups fed levels of molinasupplemented diets were characterized by significant dose-related increases in the level of serum Fe (69.11 ± 4.55 to 84.3 ± 2.12 μg/dl). In addition, there were  variable increases in the measured levels of hemoglobin (11.11 ± 1.1 to 14.25 ± 1.1 g/L), hematocrit (39.15 ± 0.15 to 42.15 ± 1.27 %) and ferritin (49.55 ± 2.25 to 65.12 ± 0.15 μg/dl) in levels of tested plantfed groups in a dose-dependent fashion compared with the control group. These data suggested that 10% of molina could provide with iron absorption and bioavailability of iron when incorporated in daily diets and therefore, could be considered as a very effective food supplement to prevent and treat anemia.

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