Potential protective Effects of okra aquatasextract against the complications of diabetes mellitus in rats

Sheteewy, Amira; Elwardany, Neveen; Abdel-Nabey, Ali

doi:10.21608/mkas.2018.158061

Potential protective Effects of okra aquatasextract against the complications of diabetes mellitus in rats

Document Type : Original research articles

Authors

10.21608/mkas.2018.158061

Abstract

The current study aimed to use different concentrations of okra aquatas extract(OAE) (15,30and 45g/100ml), in addition to whole and residues mashed okrain feeding induced diabetes rat groups for six weeks. Such groups were biologically and histopathologically compared with another negative and positive group. The proximate chemical composition as well as fiber fractions (crude,neutral detergent and acid detergent) and some minerals (Ca,Mg and Fe) of okra pods were also studied. Organoleptic evaluation of OAE was also assessed by diabetic patients. The results indicated that significant differences (P ≤ 0.05) were noted between body and organs weight especially heart and spleen of rats fed on OAE diets in comparison with the other groups. In addition, OAE enhanced insulin secretion and lowered glucose level. Also, OAE lowered TG, LDL and VLDL while the HDL, liver and kidney functions improved. Pancreatic histopathological examination showed that groups fed on OAE (30,45g/100ml) seemed to be close to the negative control group with no histopathological changes in relative to the other diabetic rat groups. The results also showed that diabetic patients preferredOAE (30g/100ml). In general addition of OAE in diets could be managed of diabetes through improve liver and kidney functions as welledpancreashistopathological.

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