Study Effect of Date Seeds Powder on Female Rats

Date palm (Phoenix dactylifera, L.) seed is a good source of mineral nutrients and phenolic compounds. In this study, the changes in minerals, antioxidant compounds (phenolics, tannins, and flavonoids), and phenolic profile of date seeds were investigated. This study aimed to study effect of date seeds powder on female rats, identify the histopathological effects of date seeds on ovaries, uterus and liver organs. Evaluation of some biochemical analysis such as HGP, some liver functions, blood lipids, sugar accumulative, feed efficiency rate, body weight gain and some internal organs weight in tested albino rats were also measured. Evaluation of some active compounds such as phenolic compounds. Phytoestrogen of date seeds powder using HPLC were also determined. Twenty-five (25) female albino rats (Sprague - Dawley strain) weighing (150±10 g)divided to 5 groups (5 rats each). The first group fed on standard diet; the second; third; fourth and fifth groups fed standard diet containing 5, 10, 15 and 20% date seeds powder, respectively. After 28 days form ingesting diets results were recorded. Date seeds raised female hormone and activated ovaries.10% and 15% date seeds powder were the best for liver functions such as GPT (glutamate pyruvate transaminase) and the best mean value of BWG (body weight gain). 10% date seeds powder  decreased  serum glucose level and serum lipid profile such as cholesterol, triglyceride, LDL (low density lipoprotein, VLDL (very low density lipoprotein) and  serum urea. 10% date seeds powder increased level of HDL (high density