Effect of Tamarind and Carob in Treatment of Kidney Functions Induced–Gentamicin in Rats

Document Type : Original research articles

Authors

Abstract

This study was conducted to investigate the effect of different concentrations 5% and 10% of tamarind and carob powder and their 5% mixture as powder on kidney functions in inducedwith gentamicin in rats. Thirty five white male albino rats, weighing 140-150±10g were used in this study. The rats were divided into 7 groups. Each group contains 5 rats. One was kept as a control negative group while the other groups were injected by gentamicin (10 mg/kg body weight). Glucose level, serum liver functions (ALT, AST and ALP), kidney function markers (urea, creatinine, uric acid), total cholesterol TC, triglycerides TG, and lipoproteins: (HDL-c, LDL-c, VIDL-c) were determined. The obtained results revealed that tamarind and carob powder and their mixture improved Liver functions, kidney functions, serum glucose levels, and lipid profile in rats. The best results recorded for 5% mixture and recommended for  use as a beverage drink to improve kidney functions. Also carob diet alone, seems to beof  betten action compered to tamarind diet alon.
 

Keywords

Main Subjects